look at the label, it gives you the # of days b/4 a honey flow that it has to be removed, it also recommends three feeding of a gallon of syrup, depending on how cold and how big a cluster you sort of have to guess how long it will take them to take down the syrup so that its gone by the removal date. Living in upstate N.Y. I have never been able to feed them fumidil in the spring, better to feed it to them in the fall so that you are sure that they honey doesn't get contaminated.It's still very cold here in NH. At what temperature can I start treating with Fumagilan-B? Can it be mixed into fondant?