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When treating for efb I've seen dosage should be 200mg per hive. I've also seen 250mg per hive. Which is it? Also when treating a nuc do you only give 100 mg or what? Thanks
 

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When treating for efb I've seen dosage should be 200mg per hive. I've also seen 250mg per hive. Which is it? Also when treating a nuc do you only give 100 mg or what? Thanks
ask the vet that is giving you the perscription
 

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No drug should be fed when
there is danger of contaminating the honey crop. Fol-
low the directions carefully and do not overdose. Re-
member that spores may and often do survive feeding
of these drugs and colonies may break down with dis-
ease when treatment is terminated.
Terramycin Soluble Powder is used for the prevention
of European and American foulbrood. This product is
available in a 6.4-oz packet. The package directions
can be confusing; to determine the correct application
amounts, follow these directions:
• The legal dose is 200 mg, three times, at 4–5 day
intervals.
• One package contains 10 grams (10,000 mg) of
Terramycin.
• 10,000 mg ÷ 200 = 50 treatments per package.
• 50 treatments ÷ 3 = 17, so one 6.4-oz package treats
17 colonies three times each.
The package calls for one teaspoon of Terramycin
Soluble Powder per ounce of powdered sugar. Use the
following calculations:
• One level teaspoon of Terramycin = 200 mg, or one
treatment.
• Each 6.4-oz package contains 50 treatments, so mix
one package with 50 oz (just over 3 lbs) of powdered
sugar. Store in a tightly sealed container. (Expo-
sure to air or moisture will break down Terramycin.)
• The dosage per colony is 2 tablespoons of this mix-
ture, given three times, 4–5 days apart (for a total of
600 mg per colony). Spread two tablespoons of the
Terramycin mixture over the end of the top bars in
the hive body with the most brood.
Preventative treatments can be applied to colonies in
the fall after honey supers are off and again in the
spring 45 days before putting honey supers on.
Premixed Terramycin formulations:
Terra Brood Mix®️ (Mid-Con)
Tetra Bee Mix®️ (Dadant)
Terra Patties®️ (Mann Lake)
Terra Pro®️ (Mann Lake)
Terra Brood Mix or Tetra Bee Mix. These products are
identical. This is premixed Terramycin and is used in
the prevention of American and European Foulbrood.
It takes the guesswork out of how much Terramycin
and sugar to mix together. For both products, the dos-
age is 2 tablespoons, three times, 4–5 days apart.
Spread the Terramycin mixture over the end of the top
bars in the hive body with the most brood in it. Treat
colonies in the fall after honey supers are off and again
in the spring at least 45 days before putting honey
supers on.

This is what I found. I wasn't sure either. Seems like spreading on the face of the combs would be more effective but I guess on the top bars in the way to go?
 
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