See section 6.6 of this page for ideas on large scale collection of royal jelly:Newly emerged bees have undeveloped hypopharyngeal and mandibular glands. Hypopharyngeal glands are paired glands inside worker’s head, consisting of a long central duct with many “grapes” (acini) attached. The glands will only develop after consuming a lot of pollen for the first 7-10 days. The glands first secrete the protein-rich component of royal jelly in young bees, but then secrete invertase, which is used to convert sucrose to simple sugars (fructose and glucose), in foragers. Mandibular glands are simple, sac-like structures attached to the base of each mandible. The glands secrete lipid-rich components of the royal jelly in young bees, but produce an alarm pheromone (2-heptanone) in foragers.