When using a Varrox, "upsetting the bees .....and frying a few" is a rare occurrence if you use correct practice. My bees are unperturbed by the OA, and I bet I've only fried up a couple of dozen bees in all the years and more than a thousand cycles I've done.
Also keep in mind that you cannot use OA when you have honey supers on the hive (unlike formic acid) and also that OA is much less effective when there is brood because, unlike formic acid, it doesn't kill varroa protected with the pupae under the wax cappings. For these two reasons, many people use formic acid in the warm months. But, as you well know, formic has its own drawback in that it has hard temperature upper limits which are tough to work around in the summer, in the south.
OTOH, if you have a summer dearth when honey supers can be taken off, and perhaps a dearth-prompted slow down in brooding that would be a good time to run an OA series. You just have to look over your whole bee-year and find places where you can seize just the right conditions for OA, and then build your year-long mite suppression plans around those opportunities.
Ex: where I live in the north the natural early winter brood pause happens just before a long 2-4 month period when my bees don't fly much, and rarely leave my apiary. Treatment at just the right point around that time kills nearly all the mites and then the weather prevents re-infestation. If you think about your whole year, as well as the biology of the mite's reproductive cycle, you'll likely find some windows where it will work well.
I have had a Varrox for several years and done more than a thousand treatments with it, I can recommend it wholeheartedly as being a sturdy, reliable, easy to work, tool. I use a small lawn mower battery which will run 20 cycles on a charge. If you've got more hives than that in one yard, you ought to be thinking about a ProVap. But up to about 25 hives, a Varrox is all you need. I bought a cheaper vaporizer first, not an inexpensive one, just a somewhat less expensive one. It failed after a year or two. I'd have been a $100+ ahead if I had bought a Varrox the first time, since I'd have only had to buy it once.
Nancy