One thing to consider is that there is a natural cycle with bees. Eventually, their comb gets old and nasty... the at first white comb is now black from all sorts of stuff like cocoons from the brood and such. At some point, the comb reaches the point where it is just nasty and the tree has filled up with nasty comb. Insert the horrible wax moth - if they are able to live in harmony with the bee's, these moths will remove the old nasty comb for the bees. Otherwise, the bees may run out of room and "Are you in oh F tee" (RUNOFT - Oh Brother Where Art Thou?) - otherwise known as abscond (leave). At this point the wax moths, ants and other critters move in and clean the tree out. When they are done, it will be nice and clean (relative term) and a new hive will be able to move in and repopulate. Of course, this is according to my studies, not actual experience.
It's kind of like when a city turns into a slum then goes through a cycle of urban development...