It looks like you've got plastic foundation? If so, you can just scrape off the worst of the loose wax and webbing and mold with your hive tool, scrape the frames, tap them against your palm to shake off loose debris and put back in the hive. The bees will clean it up. The very worst of the wood, if you're concerned, can be replaced by popping out the plastic foundation/comb by cutting the edges of the comb around the frame on both sides and popping it out. Then can get a new frame to pop it into.
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