Here's something I had done. All my hives are stimulated in early spring with supplement and are treated the same and are equalized so that by the last week in march they are pretty well all the same strength. there are a few that are always better then the others (go figure) and I picked out 4 hives that I would consider the best of the best. While my other hives were moved into pollination, I had kept back these 4 hives and (exploded) them towards the end of the maple/dandilion flow.
For each colony I layed out 5 nuc boxs and had an extra super with 6 frames set inside. I made up my nucs while looking for the queen. when i found the queen I set her into the super (she's on a brood frame) and give them 2 other frames from that hive that did not have brood on it. In each nuc, 3 frames of brood were given, with a least one frame capped brood and one frame with eggs (wether those eggs be few or many). the nucs were loaded up and took to another yard (that must be do to prevent bees from returning to original hive) and the super in which I put the queen was put back to the original place where the hive satto catch the feild force. (an impressive feild force it was, it equaled 4 frames of bees)
the nucs were allowed to rear there own queen. By the end of the first week in june they were transfered to singles, and about a month later they were given an excluder with a shallow which they had filled up nicely. A second brood chamber could be added instead if you wanted to overwinter a double. As it were, I overwintered them as singles and doubled them up the following spring, those were some pretty awsome hives.
So to sum it all up. it is possible to make 5 nucs from a hive with the sixth one kept back with the queen. Only, be sure that your colony is in a position that it looks like it could pop a swarm at any moment and where out of the 18 frames that are in the hive that 16 of them have brood.