A slight correction:
Sucrose is one glucose molecue and one fructose molecule covalently connected into a single molecule. It will come apart in water solution, but only if heated in the presence of acid. It contains equal parts of glucose and fructose when hydrolyzed by the acid, and this solution is called "invert sugar". HFCS and sucrose solutions are NOT the same -- sucrose is a non-reducing sugar and is much less chemically reactive than either glucose or fuctose. Bees can use either as a substitute for honey, and invert a considerable amount of the sucrose they collect in nectar (which only contains sucrose unless spoiled).
High fructose corn syrup contains much more fructose than glucose (so does honey sometimes, it varies). In highly purifed form it is fine, but when heated some of the reducing sugars get converted into hydroxymethylfurfural. This compound is highly toxic to bees and has caused problems in the past. It can form in significant quantities at temperatures as low as 120F, so a tanker sitting in the Texas sun for a day will likely have more HMF than one would desire in the syrup. HMF is brown, and so are some of the other materials formed when heating sugar syrups (think caramel), so a yellow or brownish tint indicates some heat exposure and degradation.
Kept cool during shipping, stored so it won't get exposed to excessive heat, and used promptly, it will be fine. As noted above, it's not an easy substance to use for a hobby beekeeper, it's actually easier to mix up small quantities of sucrose syrup for supplemental feeding. When you have dozens of hives, it makes more sense since it's cheaper, you don't have to mix it, and it's easily pump dispensed. You can fill feeders with a hose nozzle similar to the ones on gasoline pumps from a large tank on a truck.
As in all things with bees, it depends on the exact situation.
I will also add that if you are routinely feeding sugar syrup of any kind, you should also be checking pollen stores and feeding a protein supplement if pollen stores are low -- the bees need protein for brood, and inadequate protein in the fall will result in hive failures in the spring.
Peter