looks like a significant variation in the ages of larvae, at least one just an egg. To me it looks like cells the bees have cleaned out for some reason, then the queen has wandered back to lay in them. Queen hunting for spots to lay in amongst the capped brood suggests they are a bit shy on space in the brood nest. Without taking a good look at a frame of fresh larvae, hard to say why this one is the way it is. Could be as simple as a young queen missed a bunch of spots on the first go over the frame, could be as bad as a disease in some of the larvae, or any other of a whole variety of reasons.
I have noticed some newly hived bees, the queen will not lay great patterns right off the bat. I don't know if it is caused by lack of nurse bees or a queen just getting into laying shape. But the patterns can be open like this. Also when you have a good flow going and a batch of brood is born and the workers just dump nectar in whatever cell they want. Then when the queen comes through there can be nectar in a cell that should be polished and ready for her and is not.
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