Too late... Save the money that you would spend to treat and put it towards next springs package. Treating now is like looking for ticks after you've been diagnosed with lyme disease... the damage is already done.
I am with CP on this one.
Judging from the first bee pic, your hive is in grave trouble. You have a few cycles of bees which are sick, and thus they will not be able to care for the new larva properly. These sick bees are the now nurse bees...no healthy nurse bees, no healthy larva. My guess would be the queen is possibly compromised as well. This hive has, for sure, one if not more than one virus that has compromised the disease threshold and reeked havoc in your hive.
If you treat you will be perpetuating poor genetics. Your hive has a less than 50% chance to live and make it through the winter as well as brood up for the spring.
The cost to treat will come at a huge price, one that is more pricy than buying a package or nuc in the spring.
Have you costed out some of theses treatments, not cheap? Have you costed out the cost of a new queen which you will need?
Oh yeah...most areas are resistant to check mite and apistan.