You can't digest the wax, as mentioned, but there is always some propolis mixed in which has some antimicrobial properties, and some think it helps with allergies, maybe because there is some pollen stuck in the wax (which makes it somewhat yellow) and some in the honey that hasn't been filtered, since it's still in the comb...
We've had Jim Higgins speak a few times at our State association meetings. Jim is on the Board of the American Apitherapy Society. Because of the propolis in the wax (as MB noted), Jim recommends eating honey in the comb for a number of health reasons. At one of our meetings, he asked for volunteers with clogged sinuses and had them take a spoonful of comb honey. Within about 30 minutes, most reported that their sinuses had cleared.
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