cross-wiring foundation

I have some deep brood frames that are already cross-wired. I plan to remove the old comb and try using them as foundationless frames. Will the cross wires interfere with the bees drawing out new comb, or will the just ignore any wires and build out a full frame anyway?

Last season I tried a few half-foundation frames and liked them so well that this season I'm gonna try a few foundationless frames. I use deeps only, so want to cross-wire them for strength. What I don't know is what difference--if any--between using wire and using fishing line. I have both...