I recently read somewhere, maybe here, that queens avoid laying in comb that has previously held honey. I have never heard this before, nor have I experienced it, but I use deeps for brood and mediums for honey. I usually use a QE, but not in the winter and the queen has come up to lay in the mediums. Also, when I overwinter, most deep frames contain honey and in the spring, she happily lays up those frames.
So, obviously the queen will lay in comb that previously held honey, but does she prefer brood comb, or is this hogwash? J