I was concerned about bee keeping laws in Mississippi, so I emailed the state.
No. There are regulations that govern the labeling of honey, the sanitary requirements for selling honey, and certification is required to sell bees or queens to other beekeepers. You do not have to register your hives with the State.
Jeffrey W. Harris
Extension / Research Apiculturist
Department of Biochemistry, Molecular Biology, Entomology and Plant Pathology
Mississippi State, MS 39762