A Strong Immune Response in Young Adult Honeybees Masks Their Increased Susceptibility to Infection Compared to Older Bees
Forager bees treated with the entomopathogenic fungus Metarhizium anisopliae s.l. survived for significantly longer than house bees. More immune genes were up regulated in house bees than foragers in response to infection, but foragers were more resistant to the pathogen than house bees. We found that development from the house to forager stages resulted in increased expression of genes that regulate the production of antimicrobial proteins.
http://www.plospathogens.org/article...l.ppat.1003083