Does anybody have any experience collecting bees during the winter for the purpose of apitherapy? I'd like to set up a 4 frame observation hive indoors (with outdoor entrance) for my friend to collect bees from (approx. 20 bees a day) for his treatment during the long Canadian winter. I've never tried doing any kind of beekeeping during the winter.

Big questions:

How will indoor temperature warmth vs. outdoor chill affect the bees reproduction?
Will feeding be necessary? Will it stimulate the queen to lay? I imagine so.

Any thoughts on this absolutely welcome.
Thanks!