I would make the split, leaving the queen cell at the original location and moving the queen with a couple of frames to a new nuc on top of the first one. You may get a good queen that way, but if not, the original queen, who looks good at this point, is still around.
All of my queens are open-mated, and only once in the past several years have I had an Africanized bee problem with one of them. I know that because I sent them in to be analyzed. What I don't know is if any others are Africanized but still of acceptable temperment.
PS I have read on a recent thread about some pretty hot Minnesota Hygenics.
"I am the Good Shepherd. The Good Shepherd lays down His life for the sheep. " John 10:11